統合薬学教育研究室

昭和薬科大学研究室一覧

昭和薬科大学研究室一覧

share :

閉じる

Staff

Masatoshi KawahataAssociate Professor / Ph.D.last update : 2025.05.12

Japanese

Profile

Name
Masatoshi Kawahata
Affiliation
Laboratory of Pharmaceutical Sciences and Education
Subjects
　　
Official title
Associate Professor
Degree
Ph.D.

Papers

Download TSV file

  • [Original paper]　Overall Shape Constraint of Alternating α/β-Hybrid Peptides Containing Bicyclic β-Proline　Siyuan Wang, Yuko Otani,* Luhan Zhai, Aoze Su, Masayuki Nara, Masatoshi Kawahata, Kentaro Yamaguchi, Akane Sada, Rieko Ohki, Tomohiko Ohwada*　Org. Lett.　21　7813–7817　2019　
  • [Original paper]　Inclusion abilities towards hexyne isomers by co-crystallization with extended V-shaped host molecule　Masatoshi Kawahata,* Masahide Tominaga, Kousuke Fujimaru, Tadashi Hyodo, Kentaro Yamaguchi*　Tetrahedron　75　130576　2019　
  • [Original paper]　Hollow and Solid Spheres Assembled from Functionalized Macrocycles Containing Adamantane　Masahide Tominaga,* Nobuto Kunitomi, Kazuaki Ohara, Masatoshi Kawahata, Tsutomu Itoh, Kosuke Katagiri, Kentaro Yamaguchi*　J. Org. Chem.　84　5109–5117　2019　
  • [Original paper]　Characteristic Hydrogen Bonding Observed in the Crystals of Aromatic Sulfonamides: 1D Chain Assembly of Molecules and Chiral Discrimination on Crystallization　Shoko Kikkawa, Hyuma Masu, Kosuke Katagiri, Misaki Okayasu, Kentaro Yamaguchi, Hiroshi Danjo, Masatoshi Kawahata, Masahide Tominaga, Yoshihisa Sei, Hidemasa Hikawa, Isao Azumaya*　Cryst. Growth Des.　19　2936–2946　2019　
  • [Original paper]　Self-Assembly Behavior Shifting to Crystal Formation of Chiral Macrocyclic Tetraimines　Masahide Tominaga,* Masatoshi Kawahata, Tsutomu Itoh, Kentaro Yamaguchi*　Cryst. Growth Des.　19　1118–1124　2019　
  • [Original paper]　Copper-catalyzed three-component reaction of ethynylstibanes, organic azides, and selenium: A simple and efficient synthesis of novel selenides and diselenides having 1,2,3-triazole rings　Mizuki Yamada, Mio Matsumura, Erina Sakaki, Shih-yun Yen, Masatoshi Kawahata, Tadashi Hyodo, Kentaro Yamaguchi, Yuki Murata, Shuji Yasuike*　Tetrahedron　75　1406–1414　2019　
  • [Original paper]　Cycloalkanes and cycloalkenes in dispersive force oriented inclusion crystals by a functionalized acyclic host molecule　Tadashi Hyodo, Masatoshi Kawahata,* Yuya Hikami, Ai Komatsu, Masahide Tominaga, Kentaro Yamaguchi*　CrystEngComm　21　1548–1554　2019　
  • [Original paper]　Amide nitrogen pyramidalization changes lactam amide spinning　Yuko Otani,* Xin Liu, Hisashi Ohno, Siyuan Wang, Luhan Zhai, Aoze Su, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada*　Nat. Commun.　10　461　2019　
  • [Original paper]　Construction and structural analysis of mono- and heterobimetallic bis(titanate) molecular cages　Toshi Nakagawa, Hiroshi Danjo,* Masatoshi Kawahata, Kentaro Yamaguchi　Tetrahedron　75　315–323　2019　
  • [Original paper]　Synthesis and characterization of 20-hydroxyvitamin D3 with the A-ring modification　Toshie Fujishima,* Tsutomu Suenaga, Masatoshi Kawahata, Kentaro Yamaguchi　J. Steroid Biochem. Mol. Biol.　187　27–33　2019　
  • [Original paper]　Co-crystal screening of disubstituted adamantane molecules with N-heterocyclic moieties for hydrogen-bonded arrays　Masatoshi Kawahata,* Masahide Tominaga, Yuki Kawanishi, Kentaro Yamaguchi*　J. Mol. Struct.　1177　511-518　2019　
  • [Original paper]　Separation of p-xylene from aromatic compounds through specific inclusion by acyclic host molecule　Masatoshi Kawahata,* Tadashi Hyodo, Masahide Tominaga, Kentaro Yamaguchi*　CrystEngComm　20　5667-5671　2018　
  • [Original paper]　Inclusion and selectivity of amides by p-terphenyl derivative bearing adamantanecarboxylic acid　Masatoshi Kawahata,* Kiyoe Matsui, Tadashi Hyodo, Masahide Tominaga, Kentaro Yamaguchi*　Tetrahedron　74　7089-7094　2018　
  • [Original paper]　Crystallization processes through self-assembled materials dependent on the substituents of tetrapodal adamantanes　Masahide Tominaga,* Akitaka Iekushi, Kazuaki Ohara, Masatoshi Kawahata, Tsutomu Itoh, Kentaro Yamaguchi,* Isao Azumaya*　Chem. Lett.　47　116-122　2018　
  • [Original paper]　Synthesis of various heterocycles having a dienamide moiety by ring-closing metathesis of ene-ynamides　Hideaki Wakamatsu,* Yoshimi Sasaki, Masatoshi Kawahata, Kentaro Yamaguchi, Yuichi Yoshimura*　Syhthesis　50　3467-3486　2018　
  • [Original paper]　Hydrogen-bonded structures from adamantane-based catechols　Masatoshi Kawahata,* Miku Matsuura, Masahide Tominaga,* Kosuke Katagiri, Kentaro Yamaguchi*　J. Mol. Struct.　1164　116-122　2018　
  • [Original paper]　Synthesis, structure and N-N bonding character of 1,1-disubstituted indazolium hexafluorophosphate　Yingtang Ning, Masatoshi Kawahata, Kentaro Yamaguchi, Yuko Otani, Tomohiko Ohwada*　Chem. Commun.　54　1881-1884　2018　
  • [Original paper]　Synthesis of Fully Functionalized 5-Selanyl-1,2,3-triazoles: Copper-Catalysed Three-Component Reaction of Ethynylstibanes, Organic Azides, and Diaryl Diselenides　Mizuki Yamada, Mio Matsumura, Fumina Takino, Yuki Murata, Yuka Kurata, Masatoshi Kawahata, Kentaro Yamaguchi, Naoki Kakusawa, Shuji Yasuike*　Eur. J. Org. Chem.　　170-177　2018　
  • [Original paper]　Comparison of the relative stability of pharmaceutical cocrystals consisting of paracetamol and dicarboxylic acids　Naoto Suzuki, Masatoshi Kawahata, Kentaro Yamaguchi, Toyofumi Suzuki, Kazuo Tomono, Toshiro Fukami*　Drug Dev. Ind. Pharm.　44　582-589　2018　
  • [Original paper]　Spherical Aggregates and Crystal Structure of Naphthalenediimide-Based Macrocycle and Complexation with Perylene　Masahide Tominaga,* Masatoshi Kawahata, Tsutomu Itoh, Kentaro Yamaguchi*　Cryst. Growth Des.　18　37-41　2018　
  • [Original paper]　Preparation and crystal structures of charge-transfer complexes of acyclic host molecules bearing pyrogallol derivatives with paraquat　Masatoshi Kawahata,* Masahide Tominaga, Yumi Maekawa, Kentaro Yamaguchi*　CrystEngComm　19　7229-7235　2017　
  • [Original paper]　Microtropins Q-W, ent-Labdane Glucosides: Microtropiosides G-I, Ursane-Type Triterpene Diglucoside and Flavonol Glycoside from the Leaves of Microtropis japonica　Saori Terazawa, Yuka Uemura, Yuka Koyama, Susumu Kawakami, Sachiko Sugimoto, Katsuyoshi Matsunami, Hideaki Otsuka,* Takakazu Shinzato, Masatoshi Kawahata, Kentaro Yamaguchi　Chem. Pharm. Bull.　65　930-939　2017　
  • [Original paper]　Proton-induced assembly?disassembly modulation of spiroborate twin-bowl polymers bearing pyridyl groups　Hiroshi Danjo,* Masahiro Hamaguchi, Kohei Asai, Mizuki Nakatani, Hiroko Kawanishi, Masatoshi Kawahata, Kentaro Yamaguchi　Macromolecules　50　8028-8032　2017　
  • [Original paper]　Antimony-lithium exchange reaction: Synthesis of 1,4,5-trisubstituted-1,2,3-triazoles by triazolyllithium with electrophiles　Mizuki Yamada, Mio Matsumura, Masatoshi Kawahata, Yuki Murata, Naoki Kakusawa, Kentaro Yamaguchi, Shuji Yasuike*　J. Organomet. Chem.　834　83-87　2017　
  • [Original paper]　Aqua coordination to attenuate the luminescence properties of europium(III)-phosphine oxide porous coordination polymers　Kosuke Katagiri,* Naoya Matsuo, Masatoshi Kawahata, Hyuma Masu, Kentaro Yamaguchi　New J. Chem.　41　8305-8311　2017　
  • [Original paper]　Revisiting secondary interactions in neighboring group participation, exemplified by reactivity changes of iminylium intermediates　Yingtang Ning, Tomoya Fukuda, Hirotaka Ikeda, Yuko Otani, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada*　Org. Biomol. Chem.　15　1381-1392　2017　
  • [Original paper]　Synthesis of 5-organostibano-1H-1,2,3-triazoles by Cu-catalyzed azide-alkyne cycloaddition and their application in the acyl-induced deantimonation for the preparation of fully substituted 5-acyl-1,2,3-triazoles　Mizuki Yamada, Mio Matsumura, Yuki Murata, Masatoshi Kawahata, Kohki Saito, Naoki Kakusawa, Kentaro Yamaguchi, Shuji Yasuike*　Tetrahedron　73　2614-2622　2017　
  • [Original paper]　Copper-catalyzed tandem cyclization of 2-(2-iodophenyl)imidazo[1,2-a]pyridine derivatives with selenium: Synthesis of benzo[b]selenophene-fused imidazo[1,2-a]pyridines　Mio Matsumura, Yumi Sakata, Atsuya Iwase, Masatoshi Kawahata, Yuki Kitamura, Yuki Murata, Naoki Kakusawa, Kentaro Yamaguchi, Shuji Yasuike*　Tetrahedron Lett.　57　5484-5488　2016　
  • [Original paper]　High-resolution X-ray structure of methyl salicylate, a time-honored oily medicinal drug, solved by crystalline sponge method　Masatoshi Kawahata,* Shinsuke Komagawa, Kazuaki Ohara, Makoto Fujita, Kentaro Yamaguchi*　Tetrahedron Lett.　57　4633-4636　2016　
  • [Original paper]　Stille coupling via C-N bond cleavage　Dong-Yu Wang, Masatoshi Kawahata, Ze-Kun Yang, Kazunori Miyamoto, Shinsuke Komagawa, Kentaro Yamaguchi,* Chao Wang,* Masanobu Uchiyama*　Nat. Commun.　7　12937　2016　
  • [Original paper]　Molecular Gyrotops with a Five-Membered Heteroaromatic Ring: Synthesis, Temperature-Dependent Orientation of Dipolar Rotors inside the Crystal, and its Birefringence Change　Toshiyuki Masuda, Junko Arase, Yusuke Inagaki, Masatoshi Kawahata, Kentaro Yamaguchi, Takashi Ohhara, Akiko Nakao, Hiroyuki Momma, Eunsang Kwon, Wataru Setaka*　Cryst. Growth Des.　16　4392-4401　2016　
  • [Original paper]　Coordination structure and extraction behavior of a silver ion with N-substituted-9-aza-3,6,12,15-tetrathiaheptadecanes: significant effect of Ph-C-N framework on the extractability　Satoshi Iwatsuki,* Atsushi Ichiyama, Syogo Tanooka, Mari Toyama, Kosuke Katagiri, Masatoshi Kawahata, Kentaro Yamaguchi, Hiroshi Danjo, Kenji Chayama*　Dalton Trans.　45　12548-12558　2016　
  • [Original paper]　Copper-catalyzed [3 + 2] cycloaddition of (phenylethynyl)-di-p-tolylstibane with organic azides　Mizuki Yamada, Mio Matsumura, Yuki Uchida, Masatoshi Kawahata, Yuki Murata, Naoki Kakusawa, Kentaro Yamaguchi, Shuji Yasuike*　Beilstein J. Org. Chem.　12　1309-1313　2016　
  • [Original paper]　Crotofolane-Type Diterpenoids, Crotocascarins L-Q, and a Rearranged Crotofolane-Type Diterpenoid, Neocrotocascarin, from the Stems of Croton cascarilloides　Susumu Kawanami, Masanori Inagaki, Katsuyoshi Matsunami, Hideaki Otsuka,* Masatoshi Kawahata, Kentaro Yamaguchi　Chem. Pharm. Bull.　64　1492-1498　2016　
  • [Original paper]　Spontaneous Oxygenation of Siloxy-N-silylketenimines to α-Ketoamides　Michiko Sasaki,* Masafumi Ando, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda　Org. Lett.　18　1598-1601　2016　
  • [Original paper]　Hydrogen bonding to carbonyl oxygen of nitrogen-pyramidalized amide - detection of pyramidalization direction preference by vibrational circular dichroism spectroscopy　Siyuan Wang, Tohru Taniguchi, Kenji Monde, Masatoshi Kawahata, Kentaro Yamaguchi, Yuko Otani,* Tomohiko Ohwada*　Chem. Commun.　52　4018-4021　2016　
  • [Original paper]　Synthesis, Structural Characterization and Antitumor Activity of 2-(di-p-tolylstibano)- and 2-(di-p-tolylbismuthano)-N-p-tolylbenzamide　Tohru Obata, Mio Matsumura, Masatoshi Kawahata, Shunsuke Hoshino, Mizuki Yamada, Yuki Murata, Naoki Kakusawa, Kentaro Yamaguchi,* Motohiro Tanaka,* Shuji Yasuike*　J. Organomet. Chem.　807　17-21　2016　
  • [Original paper]　Stereochemical Course of Deprotonation-Acylation of N-Boc- and N-Carbamoyl-2-cyano-6-methylpiperidines　Yuri Kotomori, Michiko Sasaki,* Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda　J. Org. Chem.　80　11013-11020　2015　
  • [Original paper]　Crotocascarins I-K: Crotofolane-Type Diterpenoids, Crotocascarin γ, Isocrotofolane Glucoside and Phenolic Glycoside from the Leaves of Croton cascarilloides　Susumu Kawakami, Katsuyoshi Matsunami, Hideaki Otsuka,* Masanori Inagaki, Yoshio Takeda, Masatoshi Kawahata, Kentaro Yamaguchi　Chem. Pharm. Bull.　63　1047-1054　2015　
  • [Original paper]　Megastigmane Glucosides and Megastigmanes from the Leaves of Meliosma lepidota ssp. Squamulata　Yuka Uemura, Mio Iwami, Susumu Kawakami, Sachiko Sugimoto, Katsuyoshi Matsunami, Hideaki Otsuka,* Takakazu Shinzato, Masatoshi Kawahata, Kentaro Yamaguchi　Chem. Pharm. Bull.　63　608-616　2015　
  • [Original paper]　A mechanistic investigation of anti-elimination in (Z)-1,2-bis(arylseleno)-1-alkenes and their sulfur analogs　Asami Tarao, Yukako Tabuchi, Eri Sugimoto, Miki Ikeda, Hitomi Uchimoto, Kenji Arimitsu, Hiroyuki Kimura, Ikuo Kawasaki, Masatoshi Kawahata, Kentaro Yamaguchi, Kiyoharu Nishide*　Org. Biomol. Chem.　13　5964-5971　2015　
  • [Original paper]　Multilayered Inclusion Nanocycles of Anionic Spiroborates　Hiroshi Danjo,* Yuki Kidena, Masatoshi Kawahata, Hiroyasu Sato, Kosuke Katagiri, Toshifumi Miyazawa, Kentaro Yamaguchi　Org. Lett.　17　2466-2469　2015　
  • [Original paper]　Nestable Tetrakis(spiroborate) Nanocycles　Hiroshi Danjo,* Yuhki Hashimoto, Yuki Kidena, Ayumi Nogamine, Kosuke Katagiri, Masatoshi Kawahata, Toshifumi Miyazawa, Kentaro Yamaguchi　Org. Lett.　17　2154-2157　2015　
  • [Original paper]　Enantioselective Synthesis of Allenylenol Silyl Ethers via Chiral Lithium Amide Mediated Reduction of Ynenoyl Silanes and Their Diels-Alder Reactions　Michiko Sasaki,* Yasuhiro Kondo, Taichi Motoishi, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda　Org. Lett.　17　1280-1283　2015　
  • [Original paper]　Formation of Lanthanide(III)-Containing Metallosupramolecular Arrays Induced by Tris(spiroborate) Twin Bowl　Hiroshi Danjo,* Toshi Nakagawa, Kosuke Katagiri, Masatoshi Kawahata, Seiki Yoshigai, Toshifumi Miyazawa, Kentaro Yamaguchi　Cryst. Growth Des.　15　384-389　2015　
  • [Original paper]　Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former　Yusuke Maeno, Toshiro Fukami,* Masatoshi Kawahata, Kentaro Yamaguchi, Tatsuaki Tagami, Tetsuya Ozeki, Toyofumi Suzuki, Kazuo Tomono　Int. J. Pharm.　473　179-186　2014　
  • [Original paper]　Robust trans-Amide Helical Structure of Oligomers of Bicyclic Mimics of β-Proline: Impact of Positional Switching of Bridgehead Substituent on Amide cis-trans Equilibrium　Siyuan Wang, Yuko Otani,* Xin Liu, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada*　J. Org. Chem.　79　5287-5300　2014　
  • [Original paper]　Enantioselective Synthesis of α-Silylamines by Meerwein-Ponndorf-Verley-Type Reduction of α-Silylimines by a Chiral Lithium Amide　Yasuhiro Kondo, Michiko Sasaki,* Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda　J. Org. Chem.　79　3601-3609　2014　
  • [Original paper]　Enantiodivergent Deprotonation/Acylation of α-Amino Nitriles　Michiko Sasaki, Tomo Takegawa, Kunihiro Sakamoto, Yuri Kotomori, Yuko Otani,* Tomohiko Ohwada, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda*　Angew. Chem. Int. Ed.　52　12956-12960　2013　
  • [Original paper]　Eight New Diterpenoids and Two New Nor-Diterpenoids from the Stems of Croton cascarilloides　Susumu Kawakami, Hiroki Toyoda, Liva Harinantenaina, Katsuyoshi Matsunami, Hideaki Otsuka,* Takakazu Shinzato, Yoshio Takeda, Masatoshi Kawahata, Kentaro Yamaguchi　Chem. Pharm. Bull.　61　411-418　2013　
  • [Original paper]　Chirality Transfer in Brook Rearrangement-mediated SE2’ Solvolytic Protonation and Its Use in Estimation of the Propensity for Racemization of the α-Lithiocarbanions of the Substituents　Michiko Sasaki, Misato Fujiwara, Yuri Kotomori, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda*　Tetrahedron　69　5823-5828　2013　
  • [Original paper]　Preparation of Tris(spiroorthocarbonate) Cyclophanes as Back to Back Ditopic Hosts　Hiroshi Danjo,* Kazuhisa Iwaso, Masatoshi Kawahata, Kazuaki Ohara, Toshifumi Miyazawa, Kentaro Yamaguchi　Org. Lett.　15　2164-2167　2013　
  • [Original paper]　Stereochemical Evidence for Stabilization of a Nitrogen Cation by Neighboring Chlorine or Bromine　Tomohiko Ohwada,* Norihiko Tani, Yuko Sakamaki, Yoji Kabasawa, Yuko Otani, Masatoshi Kawahata, Kentaro Yamaguchi*　Proc. Natl. Acad. Sci. U.S.A.　110　4206-4211　2013　
  • [Original paper]　Microtropins A-I: 6'-O-(2''S,3''R)-2''-Ethyl-2'',3''-dihydroxybutyrates of Aliphatic Alcohol β-D-glucopyranosides from the Branches of Microtropis japonica　Yuka Uemura, Sachiko Sugimoto, Katsuyoshi Matsunami, Hideaki Otsuka,* Yoshio Takeda, Masatoshi Kawahata, Kentaro Yamaguchi　Phytochemistry　87　140-147　2013